Pepsin would be most active in which location?

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Multiple Choice

Pepsin would be most active in which location?

Explanation:
Pepsin is a protease that works best in strongly acidic conditions, which are found in the stomach. It is secreted as pepsinogen and activated by the stomach’s low pH, enabling it to cleave peptide bonds in dietary proteins there. In the mouth, the environment is near neutral due to saliva, so pepsin remains inactive. In the small intestine, the pH is more alkaline, and pepsin is inactivated, while other digestive proteases take over. Thus pepsin would be most active in the stomach.

Pepsin is a protease that works best in strongly acidic conditions, which are found in the stomach. It is secreted as pepsinogen and activated by the stomach’s low pH, enabling it to cleave peptide bonds in dietary proteins there. In the mouth, the environment is near neutral due to saliva, so pepsin remains inactive. In the small intestine, the pH is more alkaline, and pepsin is inactivated, while other digestive proteases take over. Thus pepsin would be most active in the stomach.

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